1357 Construction of the atopic dermatitis sweat function registry (ADSF Registry) for sweating disturbance in atopic dermatitis evaluated by automatic assessment for skin microstructure and sweating

Sweat is important to preserve skin moisturized. However, sweat known exacerbate atopic dermatitis (AD), and only little attention has been paid the disturbance in patients with AD. To know characteristics of AD, basal thermo-reactive sweating at forearm were analyzed by Automatic Assessment for Skin Microstructure Sweating (AAMS), which quantitates perspiration captured impression mold technique. The Atopic Dermatitis Function Registry (ADSF Registry) was established cooperation 4 dermatology centers, AAMS samples 38 AD 26 age-matched healthy controls (HC) collected registered their clinical information. analysis ADSF registry revealed that mean number droplets fold resting condition low compared HC, ridges high, relation progression roughness. Moreover, did not change from baseline after thermal stimulus, whereas HC significantly increased. Thus, function impaired both conditions. using may be a powerful platform further studies patients.